Publications

2010

Brodin P, Poquet Y, Levillain F, Peguillet I, Larrouy-Maumus G, Gilleron M, Ewann F, Christophe T, Fenistein D, Jang J, Jang MS, Park SJ, Rauzier J, Carralot JP, Shrimpton R, Genovesio A, Gonzalo-Asensio JA, Puzo G, Martin C, Brosch R, Stewart GR, Gicquel B, Neyrolles O. High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling.. PloS Pathogens Sep 9;6(9). pii: e1001100 (2010)

Christophe T, Ewann F, Jeon HK, Cechetto J, Brodin P. High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery.. Future Medicinal Chemistry, 2(8):1283-1293 (2010)

Jang J, Stella A, Boudou F, Levillain F, Darthuy E, Vaubourgeix J, Wang C, Bardou F, Puzo G, Gilleron M, Burlet-Schiltz O, Monsarrat B, Brodin P, Gicquel B, Neyrolles O. Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ. Microbiology 156(Pt 6):1619-31 (2010)


2009

Christophe T, Jackson M, Jeon HK, Fenistein D, Contreras-Dominguez M, Kim J, Genovesio A, Carralot JP, Ewann F, Kim EH, Lee SY, Kang S, Seo MJ, Park EJ, Skovierová H, Pham H, Riccardi G, Nam JY, Marsollier L, Kempf M, Joly-Guillou ML, Oh T, Shin WK, No Z, Nehrbass U, Brosch R, Cole ST, Brodin P. High content screening identifies decaprenyl-phosphoribose 2′ epimerase as a target for intracellular antimycobacterial inhibitors. PloS Pathogens Oct;5(10):e1000645 (2009)

Morille M., Montier T., Legras P., Carmoy N., Brodin P., Pitard B., Benoit J-P. and Passirani C. Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting. Biomaterials 2009 Sep 30. [Epub ahead of print] (2009)

Bitter W., Houben E.N.G., Bottai D., Brodin P., Eric J. Brown, Jeffrey S. Cox, Keith Derbyshire, Sarah M. Fortune, Lian-Yong Gao, Jun Liu, Nicolaas C. Gey van Pittius, Alexander S. Pym, Eric J. Rubin, David R. Sherman ,Stewart T. Cole and Roland Brosch. Systematic genetic nomenclature for type VII secretion systems. PloS Pathogens Oct;5(10):e1000507 (2009)

Makarov, V.; Manina, G.; Mikusova, K.; Mollmann, U.; Ryabova, O.; Saint-Joanis, B.; Dhar, N.; Pasca, M. R.; Buroni, S.; Lucarelli, A. P.; Milano, A.; De Rossi, E.; Belanova, M.; Bobovska, A.; Dianiskova, P.; Kordulakova, J.; Sala, C.; Fullam, E.; Schneider, P.; McKinney, J. D.; Brodin, P.; Christophe, T.; Waddell, S.; Butcher, P.; Albrethsen, J.; Rosenkrands, I.; Brosch, R.; Nandi, V.; Bharath, S.; Gaonkar, S.; Shandil, R. K.; Balasubramanian, V.; Balganesh, T.; Tyagi, S.; Grosset, J.; Riccardi, G. & Cole, S. T. Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis. Science May 8, 32455928-.801-4 (2009)

Carralot J.P., Kim T.K., Lenseigne B., Genovesio A. & Brodin P. Automated High-Throughput siRNA Transfection in Raw 264.7 macrophages: A Case Study for Optimization Procedure. Journal of Biomolecular Screening Feb;14(2):151-60 (2009).

 

2008

Fenistein D., Lenseigne B., Christophe T., Brodin P. & Genovesio A. A fast fully automated cell segmentation algorithm for high throughput and high content screening.. Cytometry A 73(10):958-64 (2008).

Frigui W., Bottai D., Majlessi L., Monot M., Josselin E., Brodin P., Garnier T., Martin C., Leclerc C., Cole, S.T. & Brosch R. PhoP, the two component regulator of Mycobacterium tuberculosis controls ESAT-6 secretion, specific T-cell recognition and virulence. PloS Pathogens 4(2):e33 (2008).


2007

Marsollier L., Aubry J., Milon G. & Brodin P. Aquatic insects and transmission of Mycobacterium ulcerans. Medecines Sciences (Paris). 23(6-7):572-5 (2007)

de Jonge MI, Pehau-Arnaudet G, Fretz MM, Romain F, Bottai D, Brodin P, Honore N, Marchal G Jiskoot W, England P, Cole ST & Brosch R. ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity. Journal of Bacteriology 189: 6028-34 (2007).

Marsollier L. *, P. Brodin*, M. Jackson, J. Kordulakova, P. Tafelmeyer, E. Carbonnelle, J. Aubry, G. Milon, P. Legras, J.P. Saint -Andre, C. Leroy, J. Cottin, M.L. Joly-Guillou, G. Reysset & S.T. Cole. Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli Ulcer Pathogenesis. PloS Pathogens May 4;3(5):e62 (2007). *equal contribution

Lenseigne B., P. Brodin, H. K. Jeon, T. Christophe & A. Genovesio Support Vector Machines for Automatic Detection of Tuberculosis Bacteria in Confocal Microscopy Images. ISBI’07 (2007).

Marsollier L. *, E. Deniaux*, P. Brodin*, A. Marot, C. Mbondji Wondje, J.P. Saint-André, A. Chauty, C. Johnson, F. Tekaia, E. Yeramian, P. Legras, B. Carbonnelle, G. Reysset, S. Eyangoh, G. Milon, S. T. Cole & J. Aubry. Protection against Mycobacterium ulcerans Lesion Development by Exposure to Aquatic Insect Saliva. PloS Medecine Feb 4(2):e64 (2007). *equal contribution

Prado, S., YL. Janin, B. Saint-Joanis, P. Brodin, S. Michel, M. Koch, S.T. Cole, F. Tillequin & P.E. Bost. Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues.. Bioorg Med Chem. 15: 2177-2186 (2007).


Book Chapter

P. Brodin, C. Demangel & S.T. Cole (2004) An introduction to functional genomics of the Mycobacterium tuberculosis complex. In: Tuberculosis. Eds: Cole S.T., Jacobs W.R. Jr American Society for Microbiology.

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