Publications

2015

Fougeron D, Van Maele L, Songhet P, Cayet D, Hot D, Van Rooijen N, Mollenkopf HJ, Hardt WD, Benecke AG, Sirard JC. Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract. Vaccine. 2015 Jun 26;33(29):3331-41.

Frellstedt L, Gosset P, Kervoaze G, Hans A, Desmet C, Pirottin D, Bureau F, Lekeux P, Art T. The innate immune response of equine bronchial epithelial cells is altered by training. Vet Res. 2015 Jan 17;46:3

Goubard A, Loïez C, Abe J, Fichel C, Herwegh S, Faveeuw C, Porte R, Cayet D, Sebbane F, Penet S, Foligné B, Desreumaux P, Saito H, Sirard JC, Simonet M, Carnoy C. Superantigenic Yersinia pseudotuberculosis induces the expression of granzymes and perforin by CD4+ T cells. Infect Immun. 2015 May;83(5):2053-64

Grosbois JM, Gicquello A, Langlois C, Le Rouzic O, Bart F, Wallaert B, Chenivesse C. Long-term evaluation of home-based pulmonary rehabilitation in patients with COPD. Int J Chron Obstruct Pulmon Dis. 2015 Sep 25;10:2037-44

Guillon A, Jouan Y, Brea D, Gueugnon F, Dalloneau E, Baranek T, Henry C, Morello E, Renauld JC, Pichavant M, Gosset P, Courty Y, Diot P, Si-Tahar M. Neutrophil proteases alter the interleukin-22-receptor-dependent lung antimicrobial defence. Eur Respir J. 2015 Sep;46(3):771-82

Iraporda C, Errea A, Romanin DE, Cayet D, Pereyra E, Pignataro O, Sirard JC, Garrote GL, Abraham AG, Rumbo M. Lactate and short chain fatty acids produced by microbial fermentation downregulate proinflammatory responses in intestinal epithelial cells and myeloid cells. Immunobiology. 2015 Oct;220(10):1161-9

Lezmi G, Gosset P, Deschildre A, Abou-Taam R, Mahut B, Beydon N, de Blic J. Airway Remodeling in Preschool Children with Severe Recurrent Wheeze. Am J Respir Crit Care Med. 2015 Jul 15;192(2):164-71

Martin C, Burgel PR, Lepage P, Andréjak C, de Blic J, Bourdin A, Brouard J, Chanez P, Dalphin JC, Deslée G, Deschildre A, Gosset P, Touqui L, Dusser D. Host-microbe interactions in distal airways: relevance to chronic airway diseases. Eur Respir Rev. 2015 Mar;24(135):78-91

Matusiak M, Van Opdenbosch N, Vande Walle L, Sirard JC, Kanneganti TD, Lamkanfi M. Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1541-6.

Paget C, Chow MT, Gherardin NA, Beavis PA, Uldrich AP, Duret H, Hassane M, Souza-Fonseca-Guimaraes F, Mogilenko DA, Staumont-Sallé D, Escalante NK, Hill GR, Neeson P, Ritchie DS, Dombrowicz D, Mallevaey T, Trottein F, Belz GT, Godfrey DI, Smyth MJ. CD3bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+ T cells. Immunol Cell Biol. 2015 Feb;93(2):198-212

Pichavant M, Sharan R, Le Rouzic O, Olivier C, Hennegrave F, Rémy G, Pérez-Cruz M, Koné B, Gosset P, Just N, Gosset P. IL-22 Defect During Streptococcus pneumoniae Infection Triggers Exacerbation of Chronic Obstructive Pulmonary Disease, EBioMedicine. 2015;2(11):1686-96

Porte R, Fougeron D, Muñoz-Wolf N, Tabareau J, Georgel AF, Wallet F, Paget C, Trottein F, Chabalgoity JA, Carnoy C, Sirard JC. A Toll-Like Receptor 5 Agonist Improves the Efficacy of Antibiotics in Treatment of Primary and Influenza Virus-Associated Pneumococcal Mouse Infections. Antimicrob Agents Chemother. 2015 Oct;59(10):6064-72

Tillie-Leblond I, Bervar JF, Deschildre A. Allergic Bronchopulmonary Mycosis. Orphan Lung Diseases. 2015;53-71

 

 

2014

Ivanov S, Paget C, Trottein F. Role of non-conventional T lymphocytes in respiratory infections: the case of the pneumococcus. PLoS Pathog. 2014 Oct 9;10(10):e1004300

Kim HY, Lee HJ, Chang YJ, Pichavant M, Shore SA, Fitzgerald KA, Iwakura Y, Israel E, Bolger K, Faul J, DeKruyff RH, Umetsu DT. Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity. Nat Med. 2014 Jan;20(1):54-61

Chow MT, Duret H, Andrews DM, Faveeuw C, Möller A, Smyth MJ, Paget C. Type I NKT-cell-mediated TNF-α is a positive regulator of NLRP3 inflammasome priming. Eur J Immunol. 2014 Jul;44(7):2111-20

Macho-Fernandez E, Cruz LJ, Ghinnagow R, Fontaine J, Bialecki E, Frisch B, Trottein F, Faveeuw C. Targeted delivery of α-galactosylceramide to CD8α+ dendritic cells optimizes type I NKT cell-based antitumor responses. J Immunol. 2014 Jul 15;193(2):961-9.

Frellstedt L, Waldschmidt I, Gosset P, Desmet C, Pirottin D, Bureau F, Farnir  F, Franck T, Dupuis-Tricaud MC, Lekeux P, Art T. Training modifies innate immune  responses in blood monocytes and in pulmonary alveolar macrophages. Am J Respir Cell Mol Biol. 2014 Jul;51(1):135-42

Van Maele L, Fougeron D, Janot L, Didierlaurent A, Cayet D, Tabareau J, Rumbo  M, Corvo-Chamaillard S, Boulenouar S, Jeffs S, Vande Walle L, Lamkanfi M, Lemoine Y, Erard F, Hot D, Hussell T, Ryffel B, Benecke AG, Sirard JC. Airway structural  cells regulate TLR5-mediated mucosal adjuvant activity. Mucosal Immunol. 2014 May;7(3):489-500

Bourke CD, Nausch N, Rujeni N, Appleby LJ, Trottein F, Midzi N, Mduluza T, Mutapi F. Cytokine responses to the anti-schistosome vaccine candidate antigen glutathione-S-transferase vary with host age and are boosted by praziquantel treatment. PLoS Negl Trop Dis. 2014 May 8;8(5):e2846

Faure E, Mear JB, Faure K, Normand S, Couturier-Maillard A, Grandjean T, Balloy V, Ryffel B, Dessein R, Chignard M, Uyttenhove C, Guery B, Gosset P, Chamaillard M, Kipnis E. Pseudomonas aeruginosa type-3 secretion system dampens host defense by exploiting the NLRC4-coupled inflammasome. Am J Respir Crit Care  Med. 2014 Apr 1;189(7):799-811

Faure E, Poissy J, Goffard A, Fournier C, Kipnis E, Titecat M, Bortolotti P, Martinez L, Dubucquoi S, Dessein R, Gosset P, Mathieu D, Guery B. Distinct immune response in two MERS-CoV-infected patients: can we go from bench to bedside? PLoS One. 2014 Feb 14;9(2):e88716

Faveeuw C, Trottein F. Optimization of natural killer T cell-mediated immunotherapy in cancer using cell-based and nanovector vaccines. Cancer Res. 2014 Mar 15;74(6):1632-8

Van Maele L, Carnoy C, Cayet D, Ivanov S, Porte R, Deruy E, Chabalgoity JA, Renauld JC, Eberl G, Benecke AG, Trottein F, Faveeuw C, Sirard JC. Activation of  Type 3 innate lymphoid cells and interleukin 22 secretion in the lungs during Streptococcus pneumoniae infection. J Infect Dis. 2014 Aug 1;210(3):493-503

Mear JB, Gosset P, Kipnis E, Faure E, Dessein R, Jawhara S, Fradin C, Faure K, Poulain D, Sendid B, Guery B. Candida albicans airway exposure primes the lung innate immune response against Pseudomonas aeruginosa infection through innate lymphoid cell recruitment and interleukin-22-associated mucosal response. Infect  Immun. 2014 Jan;82(1):306-15

Pichavant M, Rémy G, Bekaert S, Le Rouzic O, Kervoaze G, Vilain E, Just N, Tillie-Leblond I, Trottein F, Cataldo D, Gosset P. Oxidative stress-mediated iNKT-cell activation is involved in COPD pathogenesis. Mucosal Immunol. 2014 May;7(3):568-78

2013

Beavis PA, Divisekera U, Paget C, Chow MT, John LB, Devaud C, Dwyer K, Stagg J, Smyth MJ, Darcy PK (2013). Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors. Proc Natl Acad Sci U S A., 110:14711-6

Paget C, Trottein F. Role of type 1 natural killer T cells in pulmonary immunity. Mucosal Immunol. 2013 Nov;6(6):1054-67

Ivanov S, Renneson J, Fontaine J, Barthelemy A, Paget C, Fernandez EM, Blanc F, De Trez C, Van Maele L, Dumoutier L, Huerre MR, Eberl G, Si-Tahar M, Gosset P, Renauld JC, Sirard JC, Faveeuw C, Trottein F. Interleukin-22 reduces lung inflammation during influenza A virus infection and protects against secondary bacterial infection. J Virol. 2013 Jun;87(12):6911-24

Crispo M, Van Maele L, Tabareau J, Cayet D, Errea A, Ferreira AM, Rumbo M and Sirard JC. 2013. Transgenic mouse model harboring the transcriptional fusion Ccl20-luciferase as a novel reporter of pro-inflammatory response. PloS One. (in press)

Auderset F, Schuster S, Fasnacht N, Coutaz M, Charmoy M, Koch U, Favre S, Wilson A, Trottein F, Alexander J, Luther SA, MacDonald HR, Radtke F, Tacchini-Cottier F. Notch signaling regulates follicular helper T cell differentiation. J Immunol. 2013 Sep 1;191(5):2344-50

van den Brule S, Huaux F, Uwambayinema F, Ibouraadaten S, Yakoub Y, Palmai-Pallag M, Trottein F, Renauld JC, Lison D. Lung Inflammation and Thymic Atrophy After Bleomycin are Controlled by the PGD2 Receptor DP1. Am J Respir Cell Mol Biol. 2013 Sep 4.

Albacker LA, Chaudhary V, Chang YJ, Kim HY, Chuang YT, Pichavant M, Dekruyff RH, Savage PB, Umetsu DT. Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity. Nat Med. 2013 Oct;19(10):1297-304

Engelmann I, Mordacq C, Tillie-Leblond I, Gosset P, Dewilde A, Pouessel G and Deschildre A. Rhinovirus and asthma:  re-infection, not persistence. Am J Respir Crit Care Med. 2013;188:1165-7

Derbise A, Pierre F, Merchez M, Pradel E, Laouami S, Ricard I, Sirard JC, Fritz J, Lemaître N, Akinbi H, Boneca IG, Sebbane F. Inheritance of the lysozyme  inhibitor Ivy was an important evolutionary step by Yersinia pestis to avoid the  host innate immune response. J Infect Dis. 2013 May 15;207(10):1535-43

Corre JP, Piris-Gimenez A, Moya-Nilges M, Jouvion G, Fouet A, Glomski IJ, Mock M, Sirard JC, Goossens PL. In vivo germination of Bacillus anthracis spores during murine cutaneous infection. J Infect Dis. 2013 Feb 1;207(3):450-7

Auderset F, Schuster S, Fasnacht N, Coutaz M, Charmoy M, Koch U, Favre S, Wilson A, Trottein F, Alexander J, Luther SA, Macdonald HR, Radtke F, Tacchini-Cottier F. Notch signaling regulates follicular helper T cell differentiation. J Immunol. 2013 Sep 1;191(5):2344-50

Breton J, Le Clère K, Daniel C, Sauty M, Nakab L, Dewulf J, Penet S, Carnoy C, Thomas P, Pot B, Nesslany F. and Foligné B. 2013. Chronic ingestion of cadmium and lead alters the bioavailability of essential and heavy metals, gene expression pathways and genotoxicity in mouse intestine. Arch. Toxicol. 2013 Oct;87(10):1787-95

van den Brule S, Huaux F, Uwambayinema F, Ibouraadaten S, Yakoub Y, Palmai-Pallag M, Trottein F, Renauld JC, Lison D. Lung Inflammation and Thymic Atrophy After Bleomycin are Controlled by the PGD2 Receptor DP1. Am J Respir Cell Mol Biol. 2013 Sep 4. [Epub ahead of print]

Montbarbon M, Pichavant M, Langlois A, Erdual E, Maggiotto F, Neut C, Mallevaey T, Dharancy S, Dubuquoy L, Trottein F, Cortot A, Desreumaux P, Gosset P, Bertin B. Colonic inflammation in mice is improved by cigarette smoke through  iNKT cells recruitment. PLoS One. 2013 Apr 25;8(4):e62208

Knudsen ML, Johansson DX, Kostic L, Nordström EK, Tegerstedt K, Pasetto A, Applequist SE, Ljungberg K, Sirard JC, Liljeström P. The adjuvant activity of alphavirus replicons is enhanced by incorporating the microbial molecule flagellin into the replicon. PLoS One. 2013 Jun 13;8(6):e65964

Moreno G, Errea A, Van Maele L, Roberts R, Léger H, Sirard JC, Benecke A, Rumbo M, Hozbor D. Toll-like receptor 4 orchestrates neutrophil recruitment into  airways during the first hours of Bordetella pertussis infection. Microbes Infect. 2013 Sep-Oct;15(10-11):708-18

Felmy B, Songhet P, Slack EMC, Mueller AJ, Kremer M, Van Maele L, Cayet D, Heikenwalder, Sirard JC, and Hardt WD. NADPH oxidase deficient mice develop colitis and bacteremia upon infection with normally avirulent, TTSS-1- and TTSS-2-deficient Salmonella Typhimurium. PloS One. 2013 Oct 15;8(10):e77204

2012

Ivanov S, Fontaine J, Paget C, Macho Fernandez E, Van Maele L, Renneson J, Maillet I, Muñoz Wolf N, Léger H, Ryffel B, Frisch B, Chabalgoity JA, Sirard JC, Benecke A, Faveeuw C, Trottein F. Key role for respiratory CD103+ dendritic cells, IFN-gamma and IL-17 in protection against Streptococcus pneumoniae infection in response to alpha-galactosylceramide. J Infect Dis. Sep 1;206(5):723-34

Nausch N, Louis D, Lantz O, Peguillet I, Trottein F, Chen IY, Appleby LJ, Bourke CD, Midzi N, Mduluza T, Mutapi F. Age-related patterns in human myeloid dendritic cell populations in people exposed to Schistosoma haematobium infection. PLoS Negl Trop Dis. 2012 Sep;6(9):e1824.

Dieudonné A, Torres D, Blanchard S, Taront S, Jeannin P, Delneste Y, Pichavant M, Trottein F, Gosset P. Scavenger receptors in human airway epithelial cells: role in response to double-stranded RNA. PLoS One. 2012;7(8):e41952

Nausch N, Bourke CD, Appleby LJ, Rujeni N, Lantz O, Trottein F, Midzi N, Mduluza T, Mutapi F. Proportions of CD4+ memory T cells are altered in individuals chronically infected with Schistosoma haematobium. Sci Rep. 2012;2:472

Paget C, Ivanov S, Fontaine J, Renneson J, Blanc F, Pichavant M, Dumoutier L,  Ryffel B, Renauld JC, Gosset P, Gosset P, Si-Tahar M, Faveeuw C, Trottein F. Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damage. J Biol Chem. 2012 Mar 16;287(12):8816-29

Macho Fernandez E, Chang J, Fontaine J, Bialecki E, Rodriguez F, Werkmeister E, Krieger V, Ehret C, Heurtault B, Fournel S, Frisch B, Betbeder D, Faveeuw C, Trottein F. Activation of invariant Natural Killer T lymphocytes in response to the α-galactosylceramide analogue KRN7000 encapsulated in PLGA-based nanoparticles and microparticles. Int J Pharm. 2012 Feb 14;423(1):45-54

Marqués JM, Rial A, Muñoz N, Pellay FX, Van Maele L, Léger H, Camou T, Sirard  JC, Benecke A, Chabalgoity JA. Protection against Streptococcus pneumoniae serotype 1 acute infection shows a signature of Th17- and IFN-γ-mediated immunity. Immunobiology. 2012 Apr;217(4):420-9

Debowski A, Carnoy C, Verbrugghe P, Nilsson H.-O, Gauntlett J.C, Fulurija A, Camilleri T, Berg DE, Marshall B. J. and Benghezal M. Xer Recombinase and genome integrity in Helicobacter pylori, a pathogen without topoisomerase IV. PloS One 2012, 7:e33310

2011

Bialecki E, Ivanov S, Fontaine J, Paget C, Vendeville C, Ehret C, Frisch B, Trottein F and Faveeuw C. Spleen-resident CD4+ and CD4- CD8a- dendritic cell subsets differ in their ability to prime invariant Natural Killer T Lymphocytes. PLoS One. 2011;6(10):e26919

Delfortrie S, Pinte S, Mattot V, Samson C, Villain G, Caetano B, Philippin-Lauridant, Baranzelli MC, Bonneterre J, Trottein F, Faveeuw C and Soncin F.  Egfl7 promotes tumor escape from immunity by repressing endothelial cell activation. Cancer Res. 2011 2011 Dec 1;71(23):7176-86

Renneson J, Guabiraba R, Maillet I, Marques RE, Ivanov S, Fontaine J, Paget C, Quesniaux V, Faveeuw C, Ryffel B, Teixeira MM, Trottein F. A Detrimental Role for Invariant Natural Killer T Cells in the Pathogenesis of Experimental Dengue Virus Infection. Am J Pathol. 2011 Oct;179(4):1872-83

Paget C, Ivanov S, Fontaine J, Blanc F, Pichavant M, Renneson J, Bialecki E, Pothlichet J, Vendeville C, Barba-Speath G, Huerre MR, Faveeuw C, Si-Tahar M, Trottein F. Potential role of invariant NKT cells in the control of pulmonary inflammation and CD8+ T cell response during acute influenza A virus H3N2 pneumonia. J Immunol. 2011 May 15;186(10):5590-602.

Lee-Chang C, Lefranc D, Salleron J, Faveeuw C, Allet C, Vermersch P, Oxombre B, Prin L. Susceptibility to experimental autoimmune encephalomyelitis is associated with altered B-cell subsets distribution and decreased serum BAFF levels. Immunol Lett. 2011 Mar 30;135(1-2):108-17

Kim HY, Eyheramonho MB, Pichavant M, Gonzalez Cambaceres C, Matangkasombut P,  Cervio G, Kuperman S, Moreiro R, Konduru K, Manangeeswaran M, Freeman GJ, Kaplan  GG, Dekruyff RH, Umetsu DT, Rosenzweig SD. A polymorphism in TIM1 is associated with susceptibility to severe hepatitis A virus infection in humans. J Clin Invest. 2011 Mar;121(3):1111-8

Dumoutier L, de Heusch M, Orabona C, Satoh-Takayama N, Eber G, Sirard JC, Di Santo JP and Renauld JC. IL-22 is produced by γC-independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS-induced lethality. Eur J Immunol. 2011, Apr;41(4):1075-85.

Moreau C, Gosset P, Kluza J, Brunaud-Danel V, Lassalle P, Marchetti P, Defebvre L, Destée A, Devos D. Deregulation of the hypoxiainducible factor-1α pathway in monocytes from sporadic amyotrophic lateral sclerosis patients. Neuroscience. 2011 Jan 13;172:110-7

2010

Beauvillain C, Meloni F, Sirard JC, Blanchard S, Jarry U, Scotet M, Magistrelli G, Delneste Y, Barnaba V, Jeannin P. The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells. J Hepatol. 2010, 52:644-51.

DeKruyff RH, Bu X, Ballesteros A, Santiago C, Chim YL, Lee HH, Karisola P, Pichavant M, Kaplan GG, Umetsu DT, Freeman GJ, Casasnovas JM. T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells. J Immunol. 2010, 184:1918-30.

Dharancy S, Body-Malapel M, Louvet A, Berrebi D, Gantier E, Gosset P, Viala J, Hollebecque A, Moreno C, Philpott DJ, Girardin SE, Sansonetti PJ, Desreumaux P, Mathurin P, Dubuquoy L. Neutrophil migration during liver injury is under nucleotide-binding oligomerization domain 1 control. Gastroenterology. 2010 Apr;138(4):1546-56.

Endt K, Stecher B, Chaffron S, Slack E, Tchitchek N, Benecke A, Van Maele L, Sirard JC, Mueller AJ, Heikenwalder M, Macpherson AJ, Strugnell R, von Mering C,  Hardt WD. The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea. PLoS Pathog. 2010 Sep 9;6(9). pii: e1001097.

Gueders MM, Hirst SJ, Quesada-Calvo F, Paulissen G, Hacha J, Gilles C, Gosset P, Louis R, Foidart JM, Lopez-Otin C, Noël A, Cataldo DD. Matrix metalloproteinase-19 deficiency promotes tenascin-C accumulation and allergen-induced airway inflammation. Am J Respir Cell Mol Biol. 2010 ; 43(3):286-95.

Lee HH, Meyer EH, Goya S, Pichavant M, Kim HY, Bu X, Umetsu SE, Jones JC, Savage PB, Iwakura Y, Casasnovas JM, Kaplan G, Freeman GJ, DeKruyff RH, Umetsu DT. Apoptotic cells activate NKT cells through T cell Ig-like mucin-like-1 resulting in airway hyperreactivity. J Immunol. 2010 Nov 1;185(9):5225-35.

Loïez C, Carnoy C, Decoene C, Pradel E, Fichel C, Courcol R, Wallet F. First case of postaneurysmal prosthetic vascular infection due to a nonsuperantigenic Yersinia pseudotuberculosis strain. J Clin Microbiol. 2010 Aug;48(8):3024-6.

Marichal T, Bedoret D, Mesnil C, Pichavant M, Goriely S, Trottein F, Cataldo D, Goldman M, Lekeux P, Bureau F, Desmet CJ. Interferon response factor 3 is essential for house dust mite-induced airway allergy. J Allergy Clin Immunol. 2010 Oct;126(4):836-844.

Muñoz N, Van Maele L, Marqués JM, Rial A, Sirard JC, Chabalgoity JA. Mucosal administration of flagellin protects mice from Streptococcus pneumoniae lung infection. Infect Immun. 2010 Oct;78(10):4226-33

Songhet P, Barthel M, Röhn TA, Van Maele L, Cayet D, Sirard JC, Bachmann M, Kopf M, Hardt WD. IL-17A/F-signaling does not contribute to the initial phase of  mucosal inflammation triggered by S. Typhimurium. PLoS One. 2010 Nov 23;5(11):e13804.

Torres D, Dieudonné A, Ryffel B, Vilain E, Si-Tahar M, Pichavant M, Lassalle P, Trottein F, Gosset P. Double-Stranded RNA Exacerbates Pulmonary Allergic Reaction through TLR3: Implication of Airway Epithelium and Dendritic Cells. J Immunol. 2010, 185:451-9

Van Maele L, Carnoy C, Cayet D, Songhet P, Dumoutier L, Ferrero I, Janot L, Erard F, Bertout J, Leger H, Sebbane F, Benecke A, Renauld JC, Hardt WD, Ryffel B, Sirard JC. TLR5 Signaling Stimulates the Innate Production of IL-17 and IL-22 by CD3negCD127+ Immune Cells in Spleen and Mucosa. J Immunol. 2010, 185:1177-85

2009

Betbeder D, Trottein F. The effect of alpha-galactosylceramide on the activation of Natural Killer T lymphocytes. Vaccine, 2009, 27:3691.

Bialecki, E, Paget, C, Fontaine, J, Capron, M, Trottein, F, and Faveeuw, C. Role of marginal zone B lymphocytes in invariant Natural Killer T cell activation. J Immunol, 2009, 82: 6105-6113.

Carnoy C, Roten CA. The dif/Xer recombination systems in proteobacteria. PLoS One, 2009, 4:e6531.

Dessein R, Gironella M, Vignal C, Peyrin-Biroulet L, Sokol H, Secher T, Lacas-Gervais S, Gratadoux JJ, Lafont F, Dagorn JC, Ryffel B, Akira S, Langella P, Nùñez G, Sirard JC, Iovanna J, Simonet M, Chamaillard M. Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis. Gut, 2009, 58:771-776.

Estrella C, Rocks N, Paulissen G, Quesada-Calvo F, Noël A, Vilain E, Lassalle P, Tillie-Leblond I, Cataldo D, Gosset P. Role of A disintegrin and metalloprotease-12 in neutrophil recruitment induced by airway epithelium. Am J Respir Cell Mol Biol, 2009, 41:449-458.

Janot L, Sirard JC, Secher T, Noulin N, Fick L, Akira S, Uematsu S, Didierlaurent A, Hussell T, Ryffel B, Erard F. Radioresistant cells expressing TLR5 control the respiratory epithelium’s innate immune responses to flagellin. Eur J Immunol, 2009, 39:1587-1596.

Kim HY, Pichavant M, Matangkasombut P, Koh YI, Savage PB, DeKruyff RH, Umetsu DT. The development of airway hyperreactivity in T-bet-deficient mice requires CD1d-restricted NKT cells. J Immunol,  2009, 182:3252-61.

Li Y, Jia Y, Pichavant M, Loison F, Sarraj B, Kasorn A, You J, Robson BE, Umetsu DT, Mizgerd JP, Ye K, Luo HR. Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia. Blood. 2009, 113:4930-41.

Matangkasombut P, Marigowda G, Ervine A, Idris L, Pichavant M, Kim HY, Yasumi T, Wilson SB, DeKruyff RH, Faul JL, Israel E, Akbari O, Umetsu DT. Natural killer T cells in the lungs of patients with asthma. J Allergy Clin Immunol. 2009, 123:1181-5.

Matangkasombut P, Pichavant M, Dekruyff RH, Umetsu DT. Natural killer T cells and the regulation of asthma. Mucosal Immunol. 2009, 2:383-92.

Moreau C, Gosset P, Brunaud-Danel V, Lassalle P, Degonne B, Destee A, Defebvre L, Devos D. CSF profiles of angiogenic and inflammatory factors depend on the respiratory status of ALS patients. Amyotroph Lateral Scler, 2009, 10:175-181.

Paget, C, Bialecki, E, Fontaine, J, vendeville, C, Mallevaey, T, Faveeuw, C and Trottein, F. Role of invariant Natural Killer T cells in immune responses to CpG oligonucleotides. J Immunol, 2009, 182:1846-1853.

Pichavant M, Matangkasombut P, Dekruyff RH, Umetsu DT. Natural killer T cells regulate the development of asthma. Expert Rev Clin Immunol. 2009, 5:251-60.

Sirard JC, Didierlaurent A, Cayet D, Sierro F, Rumbo M. Toll-like receptor 5- and lymphotoxin beta receptor-dependent epithelial Ccl20 expression involves the same NF-kappaB binding site but distinct NF-kappaB pathways and dynamics. Biochim Biophys Acta, 2009, 1789:386-394.

Taront S, Dieudonné A, Blanchard S, Jeannin P, Lassalle P, Delneste Y, Gosset P. Implication of scavenger receptors in the interactions between diesel exhaust particles and immature or mature dendritic cells. Part Fibre Toxicol, 2009, 13:6-9.

Trottein F, Schaffer L, Ivanov S, Paget C, Vendeville C, Cazet A, Groux-Degroote S, Lee S, Krzewinski-Recchi MA, Faveeuw C, Head SR, Gosset P, Delannoy P. Differential glycosyltransferase and sulfotransferase gene expression profiles in human monocytes, dendritic cells and macrophages. Glycoconjugate J, 2009, 26:1259-1274.

2008

Depontieu F, Grigoriu BD, Scherpereel A, Adam E, Delehedde M, Gosset P, Lassalle P. Loss of Endocan tumorigenic properties after alternative splicing of exon 2. BMC Cancer, 2008, 8:14.

Didierlaurent A, Goulding J, Patel S, Snelgrove R, Low L, Bebien M, Lawrence T, van Rijt LS, Lambrecht BN, Sirard JC, Hussell T. Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection. J Exp Med, 2008, 205:323.

Faveeuw, C, Mallevaey, T, and Trottein, F. Role of Natural Killer T lymphocytes during helminth infections. Parasite, 2008, 15:284-288.

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