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Daniel C, Titecat M, Poiret S, Cayet D, Boutillier D, Simonet M, Sirard JC, Lemaître N, Sebbane F. Characterization of the protective immune response to Yersinia pseudotuberculosis infection in mice vaccinated with an LcrV-secreting strain of Lactococcus lactis. Vaccine, 2016, 34: 5762–5767

Drug Design from the Cryptic Inhibitor Envelope.  Lee C.L, Liang X, Wu Q, Najeeb J, Zhao J, Gopalaswamy R, Titecat M, Sebbane F, Lemaitre N, Toone E.J., Zhou P. Nature communications, 2016, 7:10638.


A possible evolutionary scenario for the loss of opgGH in Yersinia pestis Quintard K, Dewitte A, Reboul A, Madec E, Bontemps-Gallo S, Dondeyne J, Marceau M, Simonet M, Lacroix J.M, Sebbane F. Infection and Immunity, 2015, 83:3638-47.

Superantigenic Yersinia pseudotuberculosis induces the expression of granzymes and perforin by CD4+ T Cells. Goubard A, Loïez C, Abe J, Fichel C, Herwegh S, Faveeuw C, Porte R, Cayet D, Sebbane F, Penet S, Foligné B, Desreumaux P, Saito H, Sirard J.C, Simonet M, Carnoy C.Infection and Immunity, 2015, 83:2053-64


Functional and structural analysis of HicA3-HicB3, a novel toxin-antitoxin system of Yersinia pestis. Bibi-Triki S, Li de la Sierra-Gallay I, Lazar N, Leroy A, Van Tilbeurgh H, Sebbane F, Pradel E. Journal of  Bacteriology. 2014, 96:3712-23

Yersinia pestis requires the 2-component regulatory system OmpR-EnvZ to resist innate immunity during the early and late stages of plague. Reboul A, Lemaître N, Titecat M, Merchez M, Deloison G, Ricard I, Pradel E, Marceau M, Sebbane F.  Journal of Infectious Diseases. 2014, 210:1367-75

New insights into how Yersinia pestis adapts to its mammalian host during bubonic plague. Pradel E, Lemaître N, Merchez M, Ricard I, Reboul A, Dewitte A, Sebbane F. PLoS Pathogens. 2014; 10(3):e100402


Inheritance of the lysozyme inhibitor Ivy was an important evolution step in Yersinia pestis for avoiding the host innate immune response. Pierre F*, Derbise A*, Merchez M, Pradel E, Laouami S, Ricard I, Sirard JC, Fritz J, Lemaître N, Akinbi H, Boneca IG, Sebbane F. Journal of Infectious Diseases, 2013; 207 (10):1535-43.


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Transcriptional Profiling of the Yersinia pestis Life Cycle. Hinnebusch BJ, Sebbane F, Vadyvaloo V. in Yersinia Systems Biology and Control. 2012. Chapter 1: 1-18. Caister Academic Press.

Yersinia pseudotuberculosis Gene expression in Plasma. 2012; in Yersinia Systems Biology and Control. Marceau M & Simonet M. Chapter 2:19-42. Caister Academic Press.


In silico comparison of Yersinia pestis and Yersinia pseudotuberculosis transcriptomes reveals a higher expression level of crucial virulence determinants in the plague bacillus. Chauvaux S, Dillies MA, Marceau M, Rosso ML, Rousseau S, Moszer I, Simonet M, Carniel E. International Journal of Medical Microbiology. 2011; 301(2):105-16.


Transit through the flea vector induces a pretransmission innate immunity resistance phenotype in Yersinia pestis. Vadyvaloo V, Jarrett C, Sturdevant DE, Sebbane F, Hinnebusch BJ. PLoS Pathogens. 2010; 6(2):e1000783.

Body lice, Yersinia pestis orientalis, and black death. Ayyadurai S, Sebbane F, Raoult D, Drancourt M. Emerging Infectious Diseases. 2010; 16(5):892-3.

Role of the Yersinia pestis yersiniabactin iron acquisition system in the incidence of flea-borne plague. Sebbane F, Jarrett C, Gardner D, Long D, Hinnebusch BJ. PLoS One. 2010; 5(12):e14379.

Autophagosomes can support Yersinia pseudotuberculosis replication in macrophages. Moreau K, Lacas-Gervais S, Fujita N, Sebbane F, Yoshimori T, Simonet M, Lafont F. Cellular Microbiology. 2010; 12(8):1108-23.


An iron-regulated LysR-type element mediates antimicrobial peptide resistance and virulence in Yersinia pseudotuberculosis. Arafah S, Rosso ML, Rehaume L, Hancock RE, Simonet M, Marceau M. Microbiology. 2009; 155(Pt 7):2168-81.

Protection against Yersinia pseudotuberculosis infection conferred by a Lactococcus lactis mucosal delivery vector secreting LcrV. Daniel C, Sebbane F, Poiret S, Goudercourt D, Dewulf J, Mullet C, Simonet M, Pot B.  Vaccine, 2009, 27:1141-1144

The Yersinia pestis caf1M1A1 fimbrial capsule operon promotes transmission by flea bite in a mouse model of bubonic plague. Sebbane F, Jarrett C, Gardner D, Long D, Hinnebusch BJ.  Infection and Immunity. 2009, 77:1222-1129

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