List of publications


Lefrancois LH, Bodier CC, Lecher S, Gilbert FB, Cochard T, Harichaux G, Labas V, Teixeira/Gomes AP, Rase D, Locht C, Biet F. Purification of native HBHA from Mycobacterium avium subsp. paratuberculosis. BMC Res Notes 2013 6:55.

Vermeulen F, Dirix V, Verscheure V, Damis E, Vermeylen D, Locht C, Mascart F. Persistence at one year of age of antigen/induced cellular immune responses in preterm infants vaccinated against whooping cough: Comparison of three different vaccines and effect of a booster dose. Vaccine 2013 31:1981-1986.

Kammoun H, Roux X, Raze D, Debrie AS, DeFilette M, Ysenbaert T, Mielcarek N, Saelens X, Fiers W, Locht C. Immunogenicity of live attenuated B. pertussis BPZE1 producing the universal influenza vaccine candidate M2e. PLoS One 2013 8:e59198.

Supply P, Marceau M, Mangenot S, Roche D, Rouanet C, Khanna V, Majlessi L, Criscuolo A, Tap J, Pawlik A, Fiette L, Orgeur M, Fabre M, Parmentier C, Frigui W, Simeone R, Boritsch EC, Debrie AS, Willery E, Walker D, Quail MA, Ma L, Bouchier C, Salvignol G, Sayes F, Cascioferro A, Seemann T, Barbe V, Locht C, Gutierrez MC, Leclerc C, Bentley SD, Stinear TP, Brisse S, Medigue C, Parkhill J, Cruveiller S, Brosch R. Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis. Nat Genet 2013 45:172-179.

Roetzer A, Diel R, Kohl TA, Rückert C, Nübel U, Blom J, Wirth T, Jaenicke S, Schuback S, Rüsch/Gerdes S, Supply P, Kalinowski J, Nieman S. Whole Genome Sequencing versus Traditional Genotyping for Investigation of a Mycobacterium tuberculosis Outbreak: A Longitudinal Molecular Epidemiological Study. PLoS Med 2013 10:e10011387.

Alvarez AS, Remy L, Allix/Béguec C, Ligier C, Lawrence C, Supply P, Guillemot D, Gaillard JL, Salomon J, Herrmann JL. Nostril microbial flora diversity is not predictive for acquiring methicillin sensitive or resistant Staphylococcus aureus. Clin Microb Inf In press.

Varghese B, Supply P, Allix/Beguec C, Shoukri M, Al/Omari R, Herbawi M, Al/Hajoj S. Admixed Phylogenetic Distribution of Drug Resistant Mycobacterium tuberculosis in Saudi Arabia. PLoS One 2013 8:e55598.

de Beer JL, van Ingen J, de Vries G, Erkens C, Sebek M, Mulder A, Sloot R, van den Brandt AM, Enaimi M, Kremer K, Supply P, van Soolingen D. Comparative study of IS6110 RFLP and VNTR typing of Mycobacterium tuberculosis in the Netherlands, based on a five year nationwide survey. J Clin Microbiol 2013 51:1193-1198.

Fontaine L, Goffin P, Dubout H, Delplace B, Baulard A, Lecat/Guillet N, Chambellon E, Gardan R, Hols P. Mechanism of competence activation by the ComRS signalling system in streptococci. Mol Microbiol 2013 87:1113-1132.

Jacob/Dubuisson F, Guérin J, Baelen S, Clatin B. Two/partner secretion : as simple as it sounds ? Res Microbiol 2013 164:583-595.

Stoffels K, Allix/Beguec C, Groenen G, Wanlin M, Berkvens D, Mathys V, Supply P, Fauville/Dufaux M. From multidrug/ to extensively drug/resistant tuberculosis: upward trends as seen from a 15/year nationwide study. PLoS One 2013 8:e63128.

Sloot R, Borgdorff MW, de Beer JL, van Ingen J, Supply P, van Soolingen D. Clustering of Tuberculosis Cases Based on Variable/Number Tandem/Repeat Typing  in Relation to the Population Structure of Mycobacterium tuberculosis in the Netherlands. J Clin Microbiol 2013 51:2427-2431.

Dupré E, Wohlkönig A, Herrou J, Locht C, Jacob-Dubuisson F, Antoine R. Characterization of the PAS domain in the sensor-kinase BvgS: mechanical role in signal transmission. BMC Microbiol 2013 13:172.

Dessein R, Corbière V, Nortier J, Dratwa M, Gastalello K, Pozdzik A, Lecher S, Grandbastien B, Locht C, Mascart F. Heparin-binding haemagglutinin, a new tool for the detected of latent Mycobacterium tuberculosis infection in haemodialysis patients. PLoS One 2013 8:e71088.

Lefrançois LH, Bodier CC, Cochard T, Canepa S, Raze D, Lanotte P, Sevilla IA, Stevenson K, Behr MA, Locht C, Biet F. A novel feature of Mycobacterium avium subspecies paratuberculosis highlighted by characterization of the HBHA adhesion. J Bacteriol 2013 195:4844-4853.

Varghese B, Supply P, Shoukri M, Allix-Beguec C, Memish Z, Abuljadayel N, Al-Hakeem R, Alrabiah F, Al-Hajoj S. Tuberculosis transmission among immigrants and autochthonous populations of the Eastern province of Saudi Arabia. PLoS One 2013 8:e77635.

Coitinho C, Greif G, Robello C, Laserra P, Willery E, Supply P. Rapidly progressing tuberculosis outbreak in a very low risk group. Eur Respir J 2013, in press.

Stoffels K, Allix-Beguec C, Groenen G, Wanlin M, Berkvens D, Mathys V, Supply P, Fauville-Dufaux M. From multidrug- to extensively drug-resistant tuberculosis: upward trends as seen from a 15-year nationwide study. PLoS One 2013 8:e63128.

Lim A Ng JK, Locht C, Alonso S. Protective role of adenylate cyclase in the context of a live pertussis vaccine candidate. Microbes Infect 2013, in press.

Alsteens D, Martinez N, Jamin M, Jacob-Dubuisson F. Sequential unfolding of beta helical protein by single-molecule atomic force microscopy. PLoS One 2013 8:73572.

Smits K, Pottier G, Smet J, Dirix V, Vermeulen F, De Schutter I, Carollo M, Locht C, Ausiello CM, MAscart F. Different T cell memory in preadolescents after whole-cell or acellular pertussis vaccination. Vaccine 2013, in press.

Thorstensson R, Trollfors B, Al-Tawil N, Jahnmatz M, Berström J, Ljungman M, Törner A, Wehlin L, Van Broekhoven A, Debrie AS, Mielcarek N, Locht C. A phase I clinical study of a live attenuated Bordetella pertussis vaccine – BPZE1; a single-center, double-blind, placebo-controlled, dose-escalating study of BPZE1 given intranasally to healthy adult male volunteers. PLoS One 2013, in press.

Meade BD, Plotkin SA, Locht C. Possible options for new pertussis vaccines. J Infect Dis 2013, in press.

Stylianou E, Reynolds Diogo G, Pepponi I, van Doleweerd C, Arias M, Locht C, Rider CC, Sibley L, Cutting SM, Locksley A, Ma JKC, Reljic R. Mucosal delivery of antigen-coated nanoparticles to alveolar heparin-lining induces protective immunity against tuberculosis infection in mice. Eur J Immunol 2013 in press.


Smith SG, Lecher S, Biltz R, Locht C, Dockrell HM. Broad heparin/binding haemagglutinin/specific cytokine and chemokine response in infants following Mycobacterium bovis BCG vaccination. Eur J Immunol 2012 42:2511-2522.

Flipo M, Desroses M, Lecat/Guillet N, Villemagne B, Blondiaux N, Leroux F, Piveteau C, Mathys V, Flament MP, Siepmann J, Villeret V, Wohlkönig A, Wintjens R, Soror SH, Christophe T, Jeon HK, Locht C, Brodin P, Déprez B, Baulard AR, Willand N. Ethionamide boostes. 2. Combining bioisosteric replacement and structure/based drug design to solve pharmacokinetic issues in a series of potent 1,2,4/oxodiazole EthR inhibitors. J Med Chem 2012 55:68-83.

Carette X, Blondiaux N, Willery E, Hoos S, Lecat/Guillet N, Lens Z, Wohlkönig A, Wintjens R, Soror SH, Frénois F, Dirié B, Villeret V, England P, Lippens G, Deprez B, Locht C, Willand N, Baulard AR. Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands. Nucleic Acids Res 2012 40:3018-3030.

Dirix V, Verscheure V, Vermeulen F, De Schutter I, Goetghebuer T, Locht C, Mascart F. Both CD4⁺ and CD8⁺ lymphocytes participate in the IFN/γ response to filamentous hemagglutinin from Bordetella pertussis in infants, children, and adults. Clin Dev Immunol 2012 2012:795958.

Lebrun P, Raze D, Fritzinger B, Wieruszeski JM, Biet F, Dose A, Carpentier M, Schwarzer D, Allain F, Lippens G, Locht C. Differential contribution of the repeats to heparin binding of HBHA, a major adhesin of Mycobacterium tuberculosis. PLoS One 2012 7:e32421.

Locht C, Mielcarek N. New pertussis vaccination approaches: en route to protect newborns? FEMS Immunol Med Microbiol 2012 66:121-133.

Kammoun H, Feunou PF, Foligné B, Debrie AS, Raze D, Mielcarek N, Locht C. Dual mechanism of protection by live attenuated Bordetella pertussis BPZE1 against Bordetella bronchiseptica in mice. Vaccine 2012 30:5864-5870.

Li R, Cheng C, Chong SZ, Lim AR, Goh YF, Locht C, Kemeny DM, Angeli V, Wong WS, Alonso S. Attenuated Bordetella pertussis BPZE1 protects against allergic airway inflammation and contact dermatitis in mouse models. Allergy 2012 67:1250-1258.

Corbière V, Pottier G, Bonkain F, Schepers K, Verscheure V, Lecher S, Doherty TM, Locht C, Mascart F. Risk stratification of latent tuberculosis defined by combined interferon gamma release assays. PLoS One 2012 7:e43285.

Papadimitriou K, Ferreira S, Papandreou NC, Mavrogonatou E, Supply P, Pot B, Tsakalidou E. Complete genome sequence of the dairy isolate Streptococcus macedonicus ACA/DC 198. J Bacteriol 2012 194:1838-1839.

Weniger T, Krawczyk J, Supply P, Harmsen D, Niemann S. Online tools for polyphasic analysis of Mycobacterium tuberculosis complex genotyping data: now and next. Infect Genet Evol 2012 12:748-754.

Biet F, Sevilla IA, Cochard T, Lefrancois LH, Garrido JM, Heron I, Juste RA, McLuckie J, Thibault VC, Supply P, Collins DM, Behr MA, Stevenson K. Inter/ and Intra/subtype genotypic differences that differentiate Mycobacterium avium subspecies paratuberculosis strains. BMC Microbiol 2012 12:264.

van Ingen J, Hoefsloot W, Buijtels PC, Tortoli E, Supply P, Dekhuijzen PN, Boeree MJ, van Soolingen D. Characterization of a novel variant of Mycobacterium chimaera. J Med Microbiol 2012 61:1234-1239.

Vadwai V, Shetty A, Supply P, Rodrigues C. Evaluation of 24/locus MIRU/VNTR in extrapulmonary specimens: study from a tertiary centre in Mumbai. Tuberculosis (Edinb) 2012 92:264-272.

de Beer JL, Kremer K, Kodmon C, Supply P, van Soolingen D. First worldwide proficiency study on variable/number tandem/repeat typing of Mycobacterium tuberculosis complex strains. J Clin Microbiol 2012 50:662-669.

Cowan LS, Hooks DP, Christianson S, Sharma MK, Alexander DC, Guthrie JL, Jamieson FB, Supply P, Allix/Beguec C, Cruz L, Desmond E, Kramer R, Lugo S, Rudrik J. Evaluation of mycobacterial interspersed repetitive/unit/variable/number tandem/repeat genotyping as performed in laboratories in Canada, France, and the United States. J Clin Microbiol 2012 50:1830-1831.

Fan E, Fiedler S, Jacob/Dubuisson F, Muller M. Two/partner Secretion of Gram/negative Bacteria: A Single beta/barrel Protein Enables Transport Across the Outer Membrane. J Biol Chem 2012 287:2591-2599.

Villemagne B, Crauste C, Flipo M, Baulard AR, Deprez B, Willand N. Tuberculosis: the drug development pipeline at a glance. Eur J Med Chem 2012 51:1-16.

Flipo M, Willand N, Lecat/Guillet N, Hounsou C, Desroses M, Leroux F, Lens Z, Villeret V, Wohlkönig W, Wintjens R, Christophe T, Kyoung Jeon H, Locht C, Brodin P, Baulard AR, Déprez B. Discovery of novel N/phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high/throughput secreening and synthesis. J Med Chem 2012 55:6391-6402.

Dias AA, Raze D, de Lima CS, Marques MA, Drobecq H, Debrie AS, Ribeiro/Guimaraes ML, Biet F, Pessolani MC. Mycobacterial laminin/binding histone/lile protein mediates collagen/dependent cytoadherence. Mem Inst Oswaldo Cruz 2012 107 Suppl.1:174-182.

Gaayeb L, Sarr JB, Ndiath MO, Hanon JB, Debrie AS, Seck M, Schacht AM, Remoué F, Hermann E, Riveau G. Seroprevalence of pertussis in Senegal: a prospective study. PLoS One 2012 7:e48684.

Lin T, Gao L, Zhang C, Odeh E, Jacobs MB, Coutte L, Chaconas G, Philipp MT, Norris SJ. Analysis of an ordered, comprehensive STM mutant library in infectious Borrelia burgdorferi: insights into the genes required for mouse infectivity. PLoS One 2012 7:e47532.


Lefrançois LH, Pujol C, Bodier CC, Teixeira-Gomez AP, Drobecq H, Rosso ML, Raze D, Dias AA, Hugot JP, Chacon O, Barletta RG, Locht C, Vidal-Pessolani MC, Biet F. Characterization of the Mycobacterium avium subsp. paratuberculosis laminin-binding/histone-like protein (Lbp/Hlp) which reacts with sera from patients with Crohn’s disease. Microbes Infect 2011 13:585-594.

Flipo M, Desroses M, Lecat-Guillet N, Dirie B, Carette X, Leroux F, Piveteau C, Demirkaya F, Lens Z, Rucktooa P, Villeret V, Christophe T, Jeon HK, Locht C, Brodin P, Deprez BP, Baulard A, Willand N. Ethionamide boosters: Synthesis, Biological Activity and Structure-Activity Relationships of a series of 1,2,4-oxadiazole EthR inhibitors. J Med Chem 2011 54:2994-3010.

Fedele G, Bianco M, Debrie AS, Locht C, Ausiello CM. Attenuated Bordetella pertussis vaccine candidate BPZE1 promotes human dendritic cell CCL21-induced migration and drives a Th1/Th17 response. J Immunol 2011 186:5388-5396.

Cardoso Oelemann M, Gomes HM, Willery E, Possuelo L, Batista Lima KV, Allix-Béguec C, Locht C, Goguet de la Salmonière YO, Gutierrez MC, Suffys P, Supply P. The forest behind the tree : phylogenetic exploration of a dominant Mycobacterium tuberculosis strain lineage from a high tuberculosis burden country. PLoS One 2011 6:e18256.

Baud C, Gutsche I, Willery E, de Paepe D, Drobecq H, Gilleron M, Locht C, Jamin M, Jacob/Dubuisson F. Membrane/associated DegP in Bordetella chaperones a repeat/rich secretory protein. Mol Microbiol 2011 80:1625-1636.

Hot D, Slupek S, Wulbrecht B, D’Hondt A, Hubans C, Antoine R, Locht C, Lemoine Y. Detection of small RNAs in Bordetella pertussis and identification of a novel repeated genetic element. BMC Genomics 2011 12:207.

Delattre AS, Saint N, Clantin B, Willery E, Lippens G, Locht C, Villeret V, Jacob/Dubuisson F. Substrate recognition by the POTRA domains of TpsB transporter FhaC. Mol Microbiol 2011 81:99-112.

Li R, Lim A, Ow ST, Phoon MC, Locht C, Chow VT, Alonso S. Development of live attenuated Bordetella pertussis strains expressing the universal influenza vaccine candidate M2e. Vaccine 2011 29:5502-5511.

Guerrero GG, Locht C. Recombinant HBHA boosting effect on BCG/induced immunity against Mycobacterium tuberculosis infection. Clin Dev Immunol 2011 2011:730702.

Locht C, Coutte L, Mielcarek N. The ins and outs of pertussis toxin. FEBS J 2011 278:4668-4682.

Supply P, Niemann S, Wirth T. On the mutation rates of spoligotypes and variable numbers of tandem repeat loci of Mycobacterium tuberculosis : Continued-when tuning matters. Infect Genet Evol 2011 11:1191-1191.

Cooke GS, Beaton RK, Lessells RJ, John L, Ashworth S, Kon OM, Williams OM, Supply P, Moodley P, Pym AS. International spread of MDR TB from Tugela Ferry, South Africa. Emerg Infect Dis 2011 17:2035-2037.

Bidovec-Stojkovic U, Zolnir-Dovc M, Supply P. One year nationwide evaluation of 24/locus MIRU/VNTR genotyping on Slovenian Mycobacterium tuberculosis isolates. Respir Med 2011 105 Suppl.1:S67-73.

Supply P, Niemann S, Wirth T. On the mutation rates of spoligotypes and variable numbers of tandem repeat loci of Mycobacterium tuberculosis. Infect Genet Evol 2011 11:251-252.

Bonnel D, Legouffe R, Willand N, Baulard A, Hamm G, Deprez B, Stauber J. MALDI imaging techniques dedicated to drug/distribution studies. Bioanalysis 2011 3:1399-1406.

Supply P, Niemann S, Wirth T. On the mutation rates of spoligotypes and variable numbers of tandem repeat loci of Mycobacterium tuberculosis : Continued/when tuning matters. Infect Genet Evol 2011 11:1191-1191.

Locht C, Rouanet C. New anti/tuberculosis vaccines. Arch Pediatr 2011 18:1023/1027.


Al-Hajoj SA, Akkerman O, Parwati I, al-Gamdi S, Rahim Z, van Soolingen D, van  Ingen J, Supply P, van der Zanden AG. Microevolution of Mycobacterium tuberculosis in a tuberculosis patient. J Clin Microbiol. 2010 Oct;48(10):3813-6.

Supply P, Niemann S, Wirth T. On the mutation rates of spoligotypes and variable numbers of tandem repeat loci of Mycobacterium tuberculosis. Infect Genet Evol. 2010 Dec 29.

Weniger T, Krawczyk J, Supply P, Niemann S, Harmsen D. MIRU-VNTRplus: a webtool for polyphasic genotyping of Mycobacterium tuberculosis complex bacteria. Nucleic Acids Res. 2010 Jul;38(Web Server issue):W326-31.

Allix-Béguec C, Fauville-Dufaux M, Stoffels K, Ommeslag D, Walravens K, Saegerman C, Supply P. Importance of identifying Mycobacterium bovis as a causative agent of human tuberculosis. Eur Respir J. 2010 Mar;35(3):692-4.

Piret G, Desmet R, Diesis E, Drobecq H, Segers J, Rouanet C, Debrie AS, Boukherroub R, Locht C, Melnyk O. Chips from chips: application to the study of antibody responses to methylated proteins. J Proteome Res. 2010 Dec 3;9(12):6467-78.

Desmet R, Diesis E, Drobecq H, Rouanet C, Chemlal K, Debrie AS, Hougardy JM, Mascart F, Locht C, Melnyk O. In situ chemical modification of peptide microarrays: application to the study of the antibody responses to methylated antigens. Methods Mol Biol. 2010;669:135-45. PubMed PMID: 20857363.

Feunou PF, Kammoun H, Debrie AS, Mielcarek N, Locht C. Long-term immunity against pertussis induced by a single nasal administration of live attenuated B. pertussis BPZE1. Vaccine. 2010 Oct 8;28(43):7047-53.

Willand N, Desroses M, Toto P, Dirié B, Lens Z, Villeret V, Rucktooa P, Locht C, Baulard A, Deprez B. Exploring Drug Target Flexibility Using in Situ Click Chemistry: Application to a Mycobacterial Transcriptional Regulator. ACS Chem Biol. 2010 Aug 26 5:1007-1013.

Loulergue P, Burgel PR, Carrat F, Fritzell B, Guthmann JP, Locht C, Power UF, Varon E, Dusser D, Launay O. Report of the 2nd “French Clinical Vaccinology Meeting Jean-Gerard Guillet”: immunization and respiratory diseases. Vaccine. 2010 Sep 14;28(40):6551-5.

Rouanet C, Locht C. Boosting BCG to protect against TB. Expert Rev Respir Med. 2010 Jun;4(3):339-48.

Place S, Verscheure V, de San N, Hougardy JM, Schepers K, Dirix V, Dediste A, Michel O, Drowart A, Allard SD, Doherty TM, Lecher S, Locht C, Mascart F. Heparin-binding, hemagglutinin-specific IFN-gamma synthesis at the site of infection during active tuberculosis in humans. Am J Respir Crit Care Med. 2010 Sep 15;182(6):848-54.

Guerrero GG, Debrie AS, Locht C. Boosting with mycobacterial heparin-binding haemagglutinin enhances protection of Mycobacterium bovis BCG-vaccinated newborn mice against M. tuberculosis. Vaccine. 2010 Jun 17;28(27):4340-7.

Li R, Lim A, Phoon MC, Narasaraju T, Ng JK, Poh WP, Sim MK, Chow VT, Locht C, Alonso S. Attenuated Bordetella pertussis protects against highly pathogenic influenza A viruses by dampening the cytokine storm. J Virol. 2010 Jul;84(14):7105-13.

Feunou PF, Bertout J, Locht C. T- and B-cell-mediated protection induced by novel, live attenuated pertussis vaccine in mice. Cross protection against parapertussis. PLoS One. 2010 Apr 15;5(4):e10178.

Kavanagh H, Noone C, Cahill E, English K, Locht C, Mahon BP. Attenuated Bordetella pertussis vaccine strain BPZE1 modulates allergen-induced immunity and prevents allergic pulmonary pathology in a murine model. Clin Exp Allergy. 2010Jun;40(6):933-41.

Delattre AS, Clantin B, Saint N, Locht C, Villeret V, Jacob-Dubuisson F. Functional importance of a conserved sequence motif in FhaC, a prototypic member of the TpsB/Omp85 superfamily. FEBS J. 2010, 277(22):4755-65.

Herrou J, Bompard C, Wintjens R, Dupré E, Willery E, Villeret V, Locht C, Antoine R, Jacob-Dubuisson F. Periplasmic domain of the sensor-kinase BvgS reveals a new paradigm for the Venus flytrap mechanism. Proc Natl Acad Sci U S A. 2010, 107(40):17351-5.

Clantin B, Leyrat C, Wohlkönig A, Hodak H, Ribeiro ED Jr, Martinez N, Baud C, Smet-Nocca C, Villeret V, Jacob-Dubuisson F, Jamin M. Structure and plasticity of the peptidyl-prolyl isomerase Par27 of Bordetella pertussis revealed by X-rat diffraction and small X-ray scattering. J Struct Biol, 2010, 169(3):253-65

Mielcarek N, Debrie AS, Mahieux S, Locht C. Dose-response of attenuated Bordetella pertussis BPZE1-induced protection in mice. Clin Vaccine Immunol, 2010, 17(3):317-24.

Narayanan S, Swaminathan S, Supply P, Shanmugam S, Narendran G, Hari L, Ramachandran R, Locht C, Jawahar MS, Narayanan PR Impact of HIV infection of the Recurrence of Tuberculosis in South India.. J Infect Dis, 2010, 201:691-703.

Shamputa IC, Lee J, Allix-Béguec C, Cho EJ, Lee JI, Rajan V, Lee EG, Min JH, Carroll MW, Goldfeder LC, Kim JH, Kang HS, Hwang S, Eum SY, Park SK, Lee H, Supply P, Cho SN, Via LE, Barry CE 3rd. Genetic diversity of Mycobacterium tuberculosis isolates from a tertiary care tuberculosis hospital on South Korea. J Clin Microbiol, 2010, 48:387-394.

Radomski N, Thibault VC, Karoui C, de Cruz K, Cochard T, Gutiérrez C, Supply P, Biet F, Boschiroli ML. Genotypic diversity of Mycobacterium avium subscpecies from human and animal origins, studied by MIRU-VNTR and IS1311 RFLP typing methods. J Clin Microbiol, 2010, 48(4):1026-34.

Vermeulen F, Verscheure V, Damis E, Vermeylen D, Leloux G, Dirix V, Locht C, Mascart F. Cellular immune responses of preterm infants after vaccination with whole-cell or acellular pertussis vaccines. Clin Vaccine Immunol, 2010, 17(2):258-62.


Baud C, Hodak H, Willery E, Drobecq H, Locht C, Jamin M, Jacob-Dubuisson F. Role of DegP for two-partner secretion in Bordetella. Mol Microbiol, 2009, 74:315-329.

Delbende C, Verwaerde C, Mougel A, Tranchand Bunel D. Induction of therapeutic antibodies by vaccination against external loops of tumor-associated viral latent membrane protein. J Virol, 2009, 83:11734-11745.

Dirix V, Verscheure V, Goetghebuer T, Hainaut M, Debrie AS, Locht C, Mascart F. Monocyte-derived interleukin-10 depresses the Bordetella pertussis specific gamma interferon response in vaccinated infants. Clin Vaccine Immunol, 2009, 16:1816-1821.

Dirix V, Verscheure V, Goetghebuer T, Hainaut M, Debrie AS, Locht C, Mascart F. Cytokine and antibody profiles in 1-year-old children vaccinated with either acellular or whole-cell pertussis vaccine during infancy. Vaccine, 2009, 27:6042-6047.

Doherty M, Wallis RS, Zumla A; WHO-Tropical Disease Research/European Commission joint expert consultation group. Biomarkers for tuberculosis disease status and diagnosis. Curr Opin Pulm Med, 2009, 15:181-187.

Gutierrez MC, Supply P, Brosch R. Pathogenomics of Mycobacteria. Genome Dyn, 2009, 6:198-210.

Herrou J, Debrie AS, Willery E, Renaud-Mongénie G, Locht C, Mooi F, Jacob-Dubuisson F, Antoine R. Molecular evolution of the two-component system BvgAS involved in virulence regulation in Bordetella. PLoS One, 2009, 4:e6996.

Jacob-Dubuisson F, Villeret V, Clantin B, Delattre AS, Saint N. First structural insights into the TpsB/Omp85 superfamily. Biol Chem, 2009, 390:675-684.

Juffroy O, Noël D, Delanoye A, Viltart O, Wolowczuk I, Verwaerde C. Subcutaneous graft of D1 mouse mesenchymal stem cells leads to the formation of a bone-like structure. Differentiation, 2009, 78:223-231.

Lechner M, Schmitt K, Bauer S, Hot D, Hubans C, Levillain E, Locht C, Lemoine Y, Gross R. Genomic island excisions in Bordetella petrii. BMC Microbiol, 2009, 18:141.

Mathys V, Wintjens R, Lefevre P, Bertout J, Singhal A, Kiass M, Kurepina N, Wang XM, Mathema B, Baulard A, Kreiswirth BN, Bifani P. Molecular genetics of para-aminosalicyclic acid resistance in clinical isolates and spontaneous mutants of Mycobacterium tuberculosis. Antimicrob Agents Chemother, 2009, 53:2100-2109.

Poulain R, Delcroix G, Frénois F, Aumercier M, Locht C, Villeret V, Déprez B, Baulard AR. Synthetic EthR inhibitors boost antituberculous activity of ethionamide. Nat Med, 2009, 15:537-544.

Rouanet C, Debrie AS, Lecher S, Locht C. Sybcutaneous boosting with heparin binding haemagglutinin increases BCG-induced protection against tuberculosis. Microbes Infect, 2009, 11:995-1001.

Skerry CM, Cassidy JP, English K, Feunou-Feunou P, Locht C, Mahon BP. A live attenuated Bordetella pertussis candidate vaccine does not cause disseminating infection in gamma interferon receptor knockout mice. Clin Vaccine Immunol, 2009, 16:1344-1351.

Verbelen C, Christiaens N, Alsteens D, Dupres V, Baulard AR, Dufrêne YF. Molecular mapping of lipoarabinomannans on mycobacteria. Langmuir, 2009, 25:4324-4327.

Willand N, Dirié B, Carette X, Bifani P, Singhal A, Desroses M, Leroux F, Willery E, Mathys V, Déprez- Dupres V, Verbelen C, Raze D, Lafont F, Dufrêne YF. Force spectroscopy of the interaction between mycobacterial adhesins and heparan sulphate proteoglycan receptors. Chemphyschem, 2009, 10:1672-1675.


Abgrall S, Sereni D, Autran B, Carcelain G, Bourgarit A, Lagrange PH. Anti-PGL-Tb1 responses as an indicator of the immune restoration syndrome in HIV-TB patients.Tuberculosis, 2008, 88, 453-461.

Ader F, Le Berre R, Fackeure R, Raze D, Menozzi FD, Viget N, Faure K, Kipnis E, Guery B, Jarraud S, Etienne J, Chidiac C. In vivo effect of adhesion inhibitor heparin on Legionella pneupophila pathogenesis in a murine pneumonia model. Intensive Care Med, 2008, 34:1511-1519.

Allix−Béguec C, Fauville−Dufaux M, Supply P. Three-year population-based evaluation of standardized Mycobacterial Interspersed Repetitive Unit-Variable Number of Tandem Repeat typing of Mycobacterium tuberculosis. J Clin Microbiol, 2008, 46:1398-1406.

Allix-Béguec C, Harmsen D, Weniger T, Supply P, Niemann S. Evaluation and strategy for use of MIRU-VNTRplus, a multifunctional database for online analysis of genotyping data and phylogenetic identification of Mycobacterium tuberculosis complex isolates. J Clin Microbiol, 2008, 46:2692-2699.

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